Publications

Preprints (Under review)

Jeonghwan Cheon, Se-Bum Paik
Gradual sensory maturation promotes abstract representation learning.

bioRxiv 2025.06.24.661295. (2025)

Jeonghwan Cheon, Jaehyuk Bae, Se-Bum Paik
One-Time Soft Alignment Enables Resilient Learning without Weight Transport.

arXiv 2505.20892. (2025)

Published Papers

Jeonghwan Cheon, Se-Bum Paik
Brain-Inspired Warm-Up Training with Random Noise for Uncertainty Calibration.

Nature Machine Intelligence (Accepted) (2026)

M Jeong, Seungdae Baek, Q Wang, L Yao, EJ Lee, AM Rivera, JJ Lee, H Jang, DB-Mukku, C HS Mun, T Boesen, S Nanda, CR Ku, H Dong, B Labonté, Se-Bum Paik†, BK Lim†
Distinct interneuronal dynamics selectively gate target-specific cortical projections in drug seeking.

Neuron (In press) (2026)

Minjun Kang, Seungdae Baek, Se-Bum Paik
Hard-wired visual filters for environment-agnostic object recognition.

Patterns (Accepted) (2025)

M Kang, S Kim, W Shin, K Kim, Y Jung, Woochul Choi, Se-Bum Paik, E Kim
Grin2b-mutant mice exhibit heightened remote fear via suppressed extinction and chronic amygdalar synaptic and neuronal dysfunction.

Science Advances 11(38), eadr7691. (2025)

Suhee Cho, Hyeonsu Lee, Seungdae Baek, Se-Bum Paik
Neuromimetic metaplasticity for adaptive continual learning without catastrophic forgetting.

Neural Networks 190, 107762. (2025)

Se-Bum Paik
Split-second insights from the brain's dual-stream visual system.

Neuron 112(24), 3991-3993. (2024)

Min Song*, EJ Shin*, H Seo, A Soltani, NA Steinmetz, D Lee†, MW Jung†, Se-Bum Paik†
Hierarchical gradients of multiple timescales in the mammalian forebrain.

Proceedings of the National Academy of Sciences 121(51), e2415695121. (2024)

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G Son, Y Na, Y Kim, JH Son, GD Clemenson, ST Schafer, JY Yoo, SL Parylak, A Paquola, H Do, D Kim, I Ahn, M Ju, CS Kang, Y Ju, E Jung, McDonald AH, Youngjin Park, G Kim, Se-Bum Paik, J Hur, J Kim, YM Han, SH Lee, FH Gage, JS Kim, J Han
miR-124 coordinates metabolic regulators acting at early stages of human neurogenesis.

Communications Biology 7(1), 1393. (2024)

Jeonghwan Cheon, SW Lee, Se-Bum Paik
Pretraining with random noise for fast and robust learning without weight transport.

Advances in Neural Information Processing Systems 37, 13748-13768. (2024)

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Hyeonsu Lee*, Woochul Choi*, Dongil Lee, Se-Bum Paik
Comparison of visual quantities in untrained neural networks.

Cell Reports 42(8), 112900. (2023)

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Seungdae Baek*, Youngjin Park*, Se-Bum Paik
Species-specific wiring of cortical circuits for small-world networks in the primary visual cortex.

PLOS Computational Biology 19(8), e1011343. (2023)

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B Ko, JY Yoo, T Yoo, Woochul Choi, R Dogan, K Sung, D Um, SB Lee, HJ Kim, S Lee, ST Baek, SK Park, Se-Bum Paik, TK Kim, JH Kim
Npas4-mediated dopaminergic regulation of safety memory consolidation.

Cell Reports 42(7), 112678. (2023)

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H Oh, S Lee, Y Oh, S Kim, YS Kim, Y Yang, Woochul Choi, YE Yoo, H Cho, S Lee, E Yang, W Koh, W Won, R Kim, C.J. Lee, H Kim, H Kang, JY Kim, T Ku, Se-Bum Paik, E Kim
Kv7/KCNQ potassium channels in cortical hyperexcitability and juvenile seizure-related death in Ank2-mutant mice.

Nature Communications 14, 3547. (2023)

W Kim, JJ Shin, YJ Jeong, K Kim, JW Bae, YW Noh, S Lee, Woochul Choi, Se-Bum Paik, MW Jung, E Lee, E Kim
Suppressed prefrontal neuronal firing variability and impaired social representation in IRSp53-mutant mice.

eLife 11, e74998. (2022)

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Jeonghwan Cheon*, Seungdae Baek*, Se-Bum Paik
Invariance of object detection in untrained deep neural networks.

Frontiers in Computational Neuroscience 16, 1030707. (2022)

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Seungdae Baek*, Min Song*, Jaeson Jang, Gwangsu Kim, Se-Bum Paik
Face detection in untrained deep neural networks.

Nature Communications 12, 7328. (2021)

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Gwangsu Kim, Jaeson Jang, Se-Bum Paik
Periodic clustering of simple and complex cells in visual cortex.

Neural Networks 143, 148-160. (2021)

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Lee E*, Lee S*, Shin JJ*, Woochul Choi*, C Chung, S Lee, J Kim, S Ha, R Kim, T Yoo, YE Yoo, J Kim, I Rhim, SY Lee, YW Noh, W Kim, T Lee, H Shin, IJ Cho, Deisseroth K, SJ Kim, J Park†, MW Jung†, Se-Bum Paik†, E Kim†
Excitatory synapses and gap junctions cooperate to improve Pv neuronal burst firing and cortical social cognition in Shank2-mutant mice.

Nature Communications 12, 5116. (2021)

M Jeong*, Hyeonsu Lee*, Y Kim, E Wang, Se-Bum Paik†, BK Lim†, D Kim†
Interhemispheric cortico-cortical pathway for sequential bimanual movements in mice.

eNeuro 8(4), ENEURO.0200-21.2021. (2021)

JW Bae*, H Jeong*, YJ Yoon, C Bae, Hyeonsu Lee, Se-Bum Paik, MW Jung
Parallel processing of working memory and temporal information by distinct types of cortical projection neurons.

Nature Communications 12, 4352. (2021)

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Koh HY*, Jaeson Jang*, Ju SH*, R Kim, GB Cho, DS Kim, JW Sohn†, Se-Bum Paik†, JH Lee†
Non-cell autonomous epileptogenesis in focal cortical dysplasia.

Annals of Neurology 1-15. (2021)

Youngjin Park*, Seungdae Baek*, Se-Bum Paik
A brain-inspired network architecture for cost-efficient object recognition in shallow hierarchical neural networks.

Neural Networks 134, 76-85. (2021)

Min Song*, Jaeson Jang*, Gwangsu Kim, Se-Bum Paik
Projection of orthogonal tiling from the retina to the visual cortex.

Cell Reports 34(1), 108581. (2021)

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Gwangsu Kim*, Jaeson Jang*, Seungdae Baek, Min Song, Se-Bum Paik
Visual number sense in untrained deep neural networks.

Science Advances 7(1), eabd6127. (2021)

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JH Shin, Min Song, Se-Bum Paik, MW Jung
Spatial organization of functional clusters representing reward and movement information in the striatal direct and indirect pathways.

Proceedings of the National Academy of Sciences (PNAS) 117(43), 27004-27015. (2020)

Jinwoo Kim*, Min Song*, Jaeson Jang, Se-Bum Paik
Spontaneous retinal waves can generate long-range horizontal connectivity in visual cortex.

Journal of Neuroscience 40(34), 6584-6599. (2020)

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Junho Song*, Woochul Choi*, YH Song, JH Kim, D Jeong, SH Lee, Se-Bum Paik
Precise mapping of single neurons by calibrated 3D reconstruction of brain slices reveals topographic projection in mouse visual cortex.

Cell Reports 31(8), 107682. (2020)

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H Jeong, D Kim, Min Song, Se-Bum Paik, MW Jung
Distinct roles of parvalbumin- and somatostatin-expressing neurons in flexible representation of task variables in the prefrontal cortex.

Progress in Neurobiology 187, 101773. (2020)

Jaeson Jang*, Min Song*, Se-Bum Paik
Retino-cortical mapping ratio predicts columnar and salt-and-pepper organization in mammalian visual cortex.

Cell Reports 30(10), 3270-3279. (2020)

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Liu D, Li W, Ma C, Zheng W, Yao Y, Tso CF, Zhong P, Chen X, Junho Song, Woochul Choi, Se-Bum Paik, Han H, Dan Y
A common hub for sleep and motor control in the substantia nigra.

Science 367(6476), 440-445. (2020)

Hyeonsu Lee, Woochul Choi, Youngjin Park, Se-Bum Paik
Distinct role of flexible and stable encodings in sequential working memory.

Neural Networks 121, 419-429. (2020)

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Woochul Choi, Se-Bum Paik
Intrinsic timescales of sensory integration for motion perception.

Scientific Reports 9(1), 3993. (2019)

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HY Koh, SH Kim, Jaeson Jang, H Kim, S Han, JS Lim, G Son, J Choi, BO Park, WD Heo, J Han, H Lee, D Lee, HC Kang, M Shong, Se-Bum Paik, DS Kim, JH Lee
BRAF somatic mutation contributes to intrinsic epileptogenicity in pediatric brain tumors.

Nature Medicine 24, 1662-1668. (2018)

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H Jung, H Park, Y Choi, H Kang, E Lee, H Kweon, J Roh, J Ellegood, Woochul Choi, J Kang, I Rhim, SY Choi, M Bae, S Kim, J Lee, C Chung, T Yoo, H Park, Y Kim, S Ha, S Um, S Mo, Y Kwon, W Mah, H Kim, Y Bae, Lerch J, Se-Bum Paik, E Kim
Sexually dimorphic behavior, neuronal activity, and gene expression in Chd8-mutant mice.

Nature Neuroscience 21, 1218-1228. (2018)

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Min Song*, MS Kang*, Hyeonsu Lee, Y Jeong, Se-Bum Paik
Classification of spatiotemporal neural activity patterns in brain imaging data.

Scientific Reports 8(1), 8231. (2018)

Jaeson Jang, Se-Bum Paik
Interlayer repulsion of retinal ganglion cell mosaics regulates spatial organization of functional maps in the visual cortex.

Journal of Neuroscience 37(50), 12141-12152. (2017)

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Pachaya* Sailamul, Jaeson Jang*, Se-Bum Paik
Synaptic convergence regulates synchronization-dependent spike transfer in feedforward neural networks.

Journal of Computational Neuroscience 43(3), 189-202. (2017)

J Kim, Y Kim, Nakajima Ryuichi, A Shin, M Jeong, A Park, Y Jeong, S Jo, S Yang, H Park, SH Cho, KH Cho, I Shim, J Chung, Se-Bum Paik, Augustine G, D Kim
Inhibitory basal ganglia inputs induce excitatory motor signals in the thalamus.

Neuron 95(5), 1181-1196, e8. (2017)

Youngjin Park, Woochul Choi, Se-Bum Paik
Symmetry of learning rate in synaptic plasticity modulates formation of flexible and stable memories.

Scientific Reports 7(1), 5671. (2017)

AH Park, SH Lee, Changju Lee, J Kim, HE Lee, Se-Bum Paik, KJ Lee, D Kim
Optogenetic mapping of functional connectivity in freely moving mice via insertable wrapping electrode array beneath the skull.

ACS Nano 10(2), 2791-2802. (2016)

Soyoung An, Woochul Choi, Se-Bum Paik
Development of a computational model on the neural activity patterns of a visual working memory in a hierarchical feedforward network.

Journal of the Korean Physical Society 67(10), 1713-1718. (2015)

Se-Bum Paik, Ringach DL
Link between the orientation and retinotopic maps in primary visual cortex.

Proceedings of the National Academy of Sciences 109(18), 7091-7096. (2012)

Se-Bum Paik, Ringach DL
Retinal origin of orientation maps in visual cortex.

Nature Neuroscience 14, 919-925. (2011)

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Se-Bum Paik, Glaser DA
Synaptic plasticity controls sensory responses through frequency-dependent gamma oscillation resonance.

PLOS Computational Biology 6(9) e1000927. (2010)

Se-Bum Paik, Kumar T, Glaser DA
Spontaneous Local Gamma Oscillation Selectively Enhances Neural Network Responsiveness.

PLOS Computational Biology 5(3) e1000342. (2009)